camk2a Phenotypes

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Phenotypes

Gene Literature (11)

Nucleotides (341)

Interactants (273)

XB-GENEPAGE-868352

Gene Symbol: camk2a Gene Name: calcium/calmodulin dependent protein kinase (CaM kinase) II alpha

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: camk2a assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (10 sources): Absent speech, Delayed ability to walk, Downslanted palpebral fissures, Epicanthus, Generalized hypotonia, Global developmental delay, Hypertelorism, Intellectual disability, Seizure, Strabismus
Mouse (48 sources): abnormal CNS synaptic transmission, abnormal avoidance learning behavior, abnormal contextual conditioning behavior, abnormal cued conditioning behavior, abnormal cutaneous/subcutaneous mechanoreceptor morphology, abnormal dendrite morphology, abnormal dentate gyrus morphology, abnormal depression-related behavior, abnormal excitatory postsynaptic currents, abnormal excitatory postsynaptic potential, abnormal hippocampus granule cell morphology, abnormal locomotor behavior, abnormal long term depression, abnormal long term object recognition memory, abnormal long term potentiation, abnormal neuron physiology, abnormal postsynaptic density morphology, abnormal response to social novelty, abnormal short term spatial reference memory, abnormal skin condition, abnormal spatial learning, abnormal spatial working memory, abnormal synapse morphology, abnormal synaptic plasticity, abnormal synaptic vesicle morphology, abnormal synaptic vesicle number, absent long term depression, behavior/neurological phenotype, circling, decreased anxiety-related response, decreased exploration in new environment, decreased paired-pulse facilitation, decreased survivor rate, enhanced coordination, enhanced long term potentiation, impaired contextual conditioning behavior, impaired spatial learning, impaired synaptic plasticity, increased aggression towards mice, increased cell proliferation, increased cerebral infarct size, increased thigmotaxis, increased vertical activity, nervous system phenotype, premature death, reduced long term depression, reduced long term potentiation, sporadic seizures [+]
View all ortholog results at Monarch