ccn2 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-855546

Gene Symbol: ccn2 Gene Name: cellular communication network factor 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: ccn2 assayed (8 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (46 sources): abnormal Meckel's cartilage morphology, abnormal angiogenesis, abnormal cartilage development, abnormal cervical atlas morphology, abnormal chondrocyte physiology, abnormal eye development, abnormal long bone hypertrophic chondrocyte zone, abnormal lung development, abnormal nasal capsule morphology, abnormal pharyngeal arch development, abnormal pulmonary alveolus morphology, abnormal respiratory conducting tube morphology, abnormal sternebra morphology, abnormal sternum morphology, abnormal type II pneumocyte morphology, abnormal vasculogenesis, abnormal vertebral column morphology, absent ethmoid bone, bowed fibula, cardiovascular system phenotype, chondrodystrophy, decreased angiogenesis, decreased bone mineral content, decreased embryo size, decreased lean body mass, decreased lung weight, decreased mesenchymal cell proliferation involved in lung development, decreased physiological sensitivity to xenobiotic, decreased trabecular bone thickness, delayed endochondral bone ossification, disorganized long bone epiphyseal plate, domed cranium, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, failure of palatal shelf elevation, increased long bone epiphyseal plate size, increased width of hypertrophic chondrocyte zone, kinked tail, neonatal lethality, complete penetrance, no abnormal phenotype detected, short mandible, short tail, small alveolar lamellar bodies, small lung, small lung saccule, small thoracic cavity [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (46 sources): abnormal Meckel's cartilage morphology, abnormal angiogenesis, abnormal cartilage development, abnormal cervical atlas morphology, abnormal chondrocyte physiology, abnormal eye development, abnormal long bone hypertrophic chondrocyte zone, abnormal lung development, abnormal nasal capsule morphology, abnormal pharyngeal arch development, [+]