Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (44) GO Terms (6) Nucleotides (108) Proteins (45) Interactants (871) Wiki

msx2     msh homeobox 2

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal roof of mouth morphology (2 sources), absent planum trabeculare anticum (2 sources), decreased width of the craniofacial region (2 sources), abnormal Meckel's cartilage morphology (1 source), abnormal basihyal morphology (1 source), abnormal ceratohyal morphology (1 source), abnormal infrarostral morphology (1 source), abnormal mouth morphology (1 source), abnormal palatoquadrati morphology (1 source), abnormal trabecula cranii morphology (1 source), absent suprarostral plate (1 source), decreased size of the craniofacial region (1 source), decreased size of the head mesenchyme (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: msx2 assayed (4 sources)
Computed annotations: msx2 assayed (29 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + lhx8 MO + msx2 MO (4 sources), Xla Wt + lhx8 MO + msx2 MO (1 source), Xla Wt + lhx8 MO + msx2 MO + BMS453 (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (29 sources): Aplasia cutis congenita of scalp, Bicoronal synostosis, Brachycephaly, Brachydactyly, Brachyturricephaly, Cleft palate, Cleft soft palate, Cleft upper lip, Craniosynostosis, Dermoid cyst, [+]
Mouse (70 sources): abnormal cerebellum anterior vermis morphology, abnormal cerebellum development, abnormal dermal layer morphology, abnormal ear morphology, abnormal enamel organ morphology, abnormal epidermis stratum basale morphology, abnormal eye development, abnormal frontal bone morphology, abnormal hair follicle bulb morphology, abnormal hair follicle inner root sheath morphology, [+]

View all ortholog results at Monarch