Anteverted nares, Atresia of the external auditory canal, Blepharophimosis, Brachycephaly, Brachydactyly, Bronchomalacia, Cerebellar hypoplasia, Chiari malformation, Choanal atresia, Cloverleaf skull, Cognitive impairment, Conductive hearing impairment, Conjunctivitis, Convex nasal ridge, Coronal craniosynostosis, Craniofacial dysostosis, Craniosynostosis, Delayed speech and language development, Dental crowding, Depressed nasal bridge, Diminished ability to concentrate, Dimple chin, Dolichocephaly, Downturned corners of mouth, Dysgerminoma, Ectopic posterior pituitary, Elbow ankylosis, External ear malformation, Facial asymmetry, Finger syndactyly, Flat occiput, Frontal bossing, Generalized hypotonia, Hallux valgus, Headache, Hearing impairment, High forehead, Hydrocephalus, Hypertelorism, Hypopigmented skin patches, Hypoplasia of the maxilla, Hypotonia, Increased intracranial pressure, Intellectual disability, Iris coloboma, Keratitis, Lambdoidal craniosynostosis, Limitation of joint mobility, Low-set, posteriorly rotated ears, Macrocephaly, Malar flattening, Mandibular prognathia, Melanocytic nevus, Midface retrusion, Multiple suture craniosynostosis, Narrow internal auditory canal, Narrow palate, Optic atrophy, Optic nerve hypoplasia, Pansynostosis, Pectus excavatum, Plagiocephaly, Polyhydramnios, Posterior plagiocephaly, Prominent forehead, Prominent occiput, Proptosis, Protruding ear, Ptosis, Recurrent corneal erosions, Recurrent respiratory infections, Respiratory distress, Respiratory insufficiency, Retrognathia, Round ear, Sagittal craniosynostosis, Seizure, Shallow orbits, Short columella, Short nose, Short stature, Skeletal dysplasia, Sleep apnea, Spasticity, Stomatocytosis, Strabismus, Telecanthus, Thick vermilion border, Tracheomalacia, Turricephaly, Visual impairment

abnormal spongiotrophoblast layer morphology, abnormal trophoblast giant cell morphology, abnormal vitelline vasculature morphology, absent placental labyrinth, absent umbilical cord, decreased blood urea nitrogen level, decreased embryo size, decreased embryo weight, decreased grip strength, decreased spongiotrophoblast size, delayed bone ossification, domed cranium, embryonic lethality during organogenesis, incomplete penetrance, embryonic lethality prior to tooth bud stage, failure of chorioallantoic fusion, forebrain hypoplasia, hindbrain hypoplasia, hydrometra, improved glucose tolerance, increased apoptosis, midbrain hypoplasia, no abnormal phenotype detected, open neural tube, pale yolk sac, preweaning lethality, complete penetrance, small superior vagus ganglion, urinary bladder obstruction