sftpc Phenotypes

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Phenotypes

Gene Literature (21)

Nucleotides (917)

Interactants (262)

XB-GENEPAGE-852770

Gene Symbol: sftpc Gene Name: surfactant, pulmonary-associated protein C

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: sftpc assayed (26 sources)
Computed annotations: sftpc assayed (10 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (9 sources): Clubbing, Cyanosis, Failure to thrive, Interstitial pneumonitis, Intraalveolar phospholipid accumulation, Recurrent respiratory infections, Respiratory distress, Tachypnea, Tubulointerstitial fibrosis
Mouse (16 sources): abnormal bronchus epithelium morphology, abnormal lung hysteresivity, abnormal lung interstitium morphology, abnormal lung vasculature morphology, abnormal pulmonary alveolus epithelial cell morphology, abnormal pulmonary alveolus morphology, abnormal pulmonary elastic fiber morphology, abnormal pulmonary interalveolar septum morphology, abnormal surfactant physiology, early reproductive senescence, increased airway resistance, increased alveolar lamellar body number, increased type II pneumocyte number, overexpanded pulmonary alveoli, poor grooming, respiratory system phenotype [+]
View all ortholog results at Monarch