Abnormality of the ovary, Abnormality of the respiratory system, Abnormality of the skin, Abnormality of vision, Blindness, Cerebellar hypoplasia, Cervicitis, Chronic irritative conjunctivitis, Conjunctivitis, Dandy-Walker malformation, Decreased level of plasminogen, Duodenal ulcer, Epiphora, Gastrointestinal inflammation, Gingival overgrowth, Gingivitis, Global developmental delay, Hydrocephalus, Hyperreflexia, Keratoconjunctivitis, Macrocephaly, Nephritis, Nephrolithiasis, Papule, Periodontitis, Poor wound healing, Premature loss of teeth, Recurrent bronchitis, Recurrent otitis media, Recurrent pharyngitis, Recurrent pneumonia, Recurrent upper respiratory tract infections, Stomatitis, Vaginitis

abnormal mammary gland development, abnormal mammary gland growth during lactation, abnormal microglial cell physiology, abnormal thrombosis, abnormal vagina morphology, absent corneal epithelium, cardiovascular system phenotype, decreased angiogenesis, decreased keratinocyte migration, decreased sensitivity to induced morbidity/mortality, decreased susceptibility to induced choroidal neovascularization, decreased susceptibility to neuronal excitotoxicity, decreased tumor growth/size, enlarged lymph nodes, eye inflammation, impaired wound healing, increased circulating fibrinogen level, increased hepatocyte proliferation, increased sensitivity to induced morbidity/mortality, intestinal ulcer, lactation failure, perianal ulcer, premature death, proctitis, reduced female fertility, venoocclusion