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Summary Expression Phenotypes Gene Literature (9) GO Terms (3) Nucleotides (49) Proteins (34) Interactants (19) Wiki

edn3     endothelin-3

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
absent melanophore (1 source), absent melanophore in the tail (1 source), absent tail (1 source), absent trunk region (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: edn3 assayed (2 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + edn3 MO (2 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (50 sources): Abdominal pain, Abnormal eyebrow morphology, Abnormal intestine morphology, Abnormal macular morphology, Abnormality of retinal pigmentation, Abnormality of temperature regulation, Abnormality of the autonomic nervous system, Abnormality of the cardiovascular system, Abnormality of the mouth, Abnormality of the nervous system, [+]
Mouse (13 sources): abnormal colon morphology, abnormal melanoblast morphology, abnormal melanocyte morphology, abnormal melanosome morphology, absent enteric neurons, darkened coat color, increased ear pigmentation, increased melanocyte number, increased thyroid tumor incidence, megacolon, [+]

View all ortholog results at Monarch