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Summary Expression Phenotypes Gene Literature (1) GO Terms (7) Nucleotides (49) Proteins (32) Interactants (3) Wiki

myoc     myocilin, trabecular meshwork inducible glucocorticoid response

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: myoc assayed (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (21 sources): Abnormal anterior chamber morphology, Abnormal iris vasculature, Abnormality iris morphology, Abnormality of the optic nerve, Central scotoma, Glaucoma, Glaucomatous visual field defect, High myopia, Increased cup-to-disc ratio, Myopia, [+]
Mouse (9 sources): abnormal canal of Schlemm morphology, abnormal retina inner plexiform layer morphology, abnormal retina neuronal layer morphology, abnormal trabecular meshwork morphology, no abnormal phenotype detected, ocular hypertension, optic nerve degeneration, retina ganglion cell degeneration, vision/eye phenotype

View all ortholog results at Monarch