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Summary Expression Phenotypes Gene Literature (1016) GO Terms (5) Nucleotides (437) Proteins (71) Interactants (3381) Wiki

myc     MYC proto-oncogene, bHLH transcription factor

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal brain ventricle morphology (1 source), abnormal cell division (1 source), abnormal head morphology (1 source), absent eye (1 source), increased apoptosis in animal cap (1 source), increased cell population proliferation in epithelium (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: myc manipulated (10 sources), myc assayed (13 sources)
Computed annotations: myc assayed (3 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + myc MO (11 sources), Xla Wt + Hsa.myc:GFP (3 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (16 sources): Abdominal pain, Abnormality of bone marrow cell morphology, Abnormality of the liver, Abnormality of the lymph nodes, Abnormality of the ovary, Abnormality of the pancreas, Abnormality of the spleen, Burkitt lymphoma, Decreased proportion of CD4-positive helper T cells, Gastrointestinal hemorrhage, [+]
Mouse (149 sources): abnormal T cell receptor beta chain V(D)J recombination, abnormal adipose tissue amount, abnormal angiogenesis, abnormal body length, abnormal bone mineralization, abnormal branching of the mammary ductal tree, abnormal cell morphology, abnormal cell nucleus morphology, abnormal chorion morphology, abnormal chromosome number, [+]

View all ortholog results at Monarch