kcnq2 Phenotypes

Phenotypes

XB-GENEPAGE-6047372

Gene Symbol: kcnq2 Gene Name: potassium channel, voltage gated KQT-like subfamily Q, member 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: kcnq2 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (46 sources): Abnormal cerebral white matter morphology, Abnormal globus pallidus morphology, Abnormality of movement, Abnormality of the orbital region, Abnormality of vision, Apnea, Bilateral tonic-clonic seizure, Cerebral atrophy, Cerebral edema, Choreoathetosis, Cognitive impairment, Deeply set eye, Dysesthesia, Dyskinesia, Dysphasia, Dystonia, EEG with burst suppression, Epileptic encephalopathy, Epileptic spasm, Facial erythema, Fatigue, Febrile seizure (within the age range of 3 months to 6 years), Feeding difficulties, Focal clonic seizure, Generalized hypotonia, Generalized tonic seizure, Global developmental delay, Hallucinations, Hypoplasia of the corpus callosum, Hypotonia, Hypsarrhythmia, Inability to walk, Intellectual disability, Memory impairment, Migraine, Motor delay, Myoclonus, Myokymia, Nausea and vomiting, Pallor, Poor gross motor coordination, Profound global developmental delay, Reduced consciousness, Seizure, Spasticity, Spastic tetraparesis [+]
View all ortholog results at Monarch

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Human (46 sources): Abnormal cerebral white matter morphology, Abnormal globus pallidus morphology, Abnormality of movement, Abnormality of the orbital region, Abnormality of vision, Apnea, Bilateral tonic-clonic seizure, Cerebral atrophy, Cerebral edema, Choreoathetosis, [+]