muc2 Phenotypes

Phenotypes

XB-GENEPAGE-6046885

Gene Symbol: muc2 Gene Name: mucin 2, oligomeric mucus/gel-forming

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: muc2 assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (30 sources): abnormal cell migration, abnormal colon morphology, abnormal endoplasmic reticulum morphology, abnormal enterocyte apoptosis, abnormal enterocyte morphology, abnormal enterocyte proliferation, abnormal intestinal absorption, abnormal intestinal goblet cell morphology, abnormal intestinal mucosa morphology, abnormal intestine physiology, abnormal large intestine crypts of Lieberkuhn morphology, abnormal mitochondrial crista morphology, decreased apoptosis, decreased colon length, decreased hematocrit, dilated mitochondria, enlarged lymph nodes, ileum inflammation, increased cell proliferation, increased endoplasmic reticulum stress, increased enterocyte apoptosis, increased interferon-gamma secretion, increased interleukin-1 beta secretion, increased interleukin-13 secretion, increased sensitivity to xenobiotic induced morbidity/mortality, increased susceptibility to induced colitis, increased susceptibility to weight loss, increased tumor necrosis factor secretion, intestinal ulcer, premature death [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (30 sources): abnormal cell migration, abnormal colon morphology, abnormal endoplasmic reticulum morphology, abnormal enterocyte apoptosis, abnormal enterocyte morphology, abnormal enterocyte proliferation, abnormal intestinal absorption, abnormal intestinal goblet cell morphology, abnormal intestinal mucosa morphology, abnormal intestine physiology, [+]