| Monarch Ortholog Phenotypes
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Human (19 sources):
Anterior lenticonus,
Corneal erosion,
Developmental cataract,
Diffuse leiomyomatosis,
Glomerular basement membrane lamellation,
Hypertension,
Hypoparathyroidism,
Ichthyosis,
Lenticonus,
Microscopic hematuria,
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Mouse (27 sources):
abnormal glomerular capillary morphology,
abnormal kidney morphology,
abnormal lens capsule morphology,
abnormal renal glomerular capsule morphology,
abnormal renal glomerulus basement membrane morphology,
abnormal renal glomerulus morphology,
abnormal renal tubule morphology,
decreased circulating fructosamine level,
decreased erythrocyte cell number,
decreased hematocrit,
decreased hemoglobin content,
decreased mean corpuscular hemoglobin,
decreased mean corpuscular volume,
dilated glomerular capillary,
dilated renal tubules,
increased circulating amylase level,
increased circulating creatinine level,
increased large unstained cell number,
increased mesangial cell number,
increased neutrophil cell number,
increased red blood cell distribution width,
increased renal glomerulus basement membrane thickness,
increased spleen weight,
pale kidney,
podocyte foot process effacement,
premature death,
renal glomerular synechia
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.