Monarch Ortholog Phenotypes
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Human (58 sources):
Abdominal pain,
Abnormal T-wave,
Abnormal autonomic nervous system physiology,
Abnormal cardiac exercise stress test,
Abnormality of neutrophils,
Abnormality of prenatal development or birth,
Abnormality of the ear,
Arrhythmia,
Atrial fibrillation,
Atrial flutter,
Atrial standstill,
Atrioventricular block,
Bundle branch block,
Cardiac arrest,
Complete heart block with broad QRS complexes,
Congestive heart failure,
Dilated cardiomyopathy,
Dyspnea,
EMG abnormality,
Elevated circulating creatine kinase concentration,
First degree atrioventricular block,
Heart block,
Hypokalemia,
Left anterior fascicular block,
Left atrial enlargement,
Left bundle branch block,
Left posterior fascicular block,
Left ventricular hypertrophy,
Lipoatrophy,
Myopathy,
Palmoplantar keratoderma,
Palpitations,
Paroxysmal atrial fibrillation,
Paroxysmal atrial tachycardia,
Paroxysmal ventricular tachycardia,
Premature atrial contractions,
Premature ventricular contraction,
Prolonged QT interval,
Prolonged QTc interval,
Reduced systolic function,
Right bundle branch block,
ST segment elevation,
Seizure,
Sensorineural hearing impairment,
Sick sinus syndrome,
Sinus bradycardia,
Stroke,
Sudden cardiac death,
Supraventricular tachycardia,
Syncope,
Tachycardia,
Torsade de pointes,
Tricuspid regurgitation,
Trifascicular block,
Ventricular arrhythmia,
Ventricular escape rhythm,
Ventricular fibrillation,
Vertigo
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Mouse (36 sources):
abnormal QT interval,
abnormal T wave,
abnormal action potential,
abnormal atrioventricular bundle conduction,
abnormal atrioventricular node conduction,
abnormal cardiac muscle contractility,
abnormal heart echocardiography feature,
abnormal heart rate,
abnormal impulse conducting system conduction,
abnormal mycoardial fiber sodium currents,
abnormal myocardial fiber physiology,
abnormal sinoatrial node conduction,
abnormal trabecula carnea morphology,
cardiac fibrosis,
cardiovascular system phenotype,
decreased cardiac muscle contractility,
decreased embryo size,
decreased myocardial fiber number,
dilated heart left ventricle,
dilated heart ventricle,
embryo tissue necrosis,
embryonic lethality during organogenesis, complete penetrance,
enlarged myocardial fiber,
increased heart weight,
increased lung weight,
increased sensitivity to induced morbidity/mortality,
liver vascular congestion,
no abnormal phenotype detected,
postnatal lethality, incomplete penetrance,
premature death,
prenatal lethality, complete penetrance,
prolonged P wave,
prolonged PQ interval,
prolonged QRS complex duration,
shortened QRS complex duration,
thick ventricular wall
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View all ortholog results at Monarch
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