| Monarch Ortholog Phenotypes
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Human (28 sources):
Abnormality of extrapyramidal motor function,
Aggressive behavior,
Akinesia,
Apathy,
Behavioral abnormality,
Cerebellar atrophy,
Cerebellar vermis atrophy,
Cognitive impairment,
Cogwheel rigidity,
Diplopia,
Dysarthria,
Dysgraphia,
Gait ataxia,
Global developmental delay,
Hyporeflexia,
Impulsivity,
Intellectual disability,
Intermittent microsaccadic pursuits,
Limb ataxia,
Microsaccadic pursuit,
Nystagmus,
Parkinsonism,
Postural tremor,
Progressive cerebellar ataxia,
Rigidity,
Scanning speech,
Slow saccadic eye movements,
Tremor
[+]
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|
Mouse (9 sources):
abnormal exploration in a new environment,
abnormal grip strength,
abnormal locomotor activation,
abnormal locomotor behavior,
decreased anxiety-related response,
decreased grip strength,
increased circulating alkaline phosphatase level,
increased exploration in new environment,
increased liver weight
|
View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.