rapgef3 Phenotypes

XB-GENEPAGE-5955479

Gene Symbol: rapgef3 Gene Name: Rap guanine nucleotide exchange factor 3

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: rapgef3 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (20 sources): abnormal adipose tissue development, abnormal pancreatic beta cell physiology, cardiovascular system phenotype, decreased blood urea nitrogen level, decreased circulating glucose level, decreased epididymal fat pad weight, decreased food intake, decreased insulin secretion, decreased neuron apoptosis, decreased white fat cell size, hematopoietic system phenotype, improved glucose tolerance, increased insulin sensitivity, increased pancreatic alpha cell number, increased respiratory quotient, increased susceptibility to diet-induced obesity, insulitis, nervous system phenotype, pancreatic islet hyperplasia, slow postnatal weight gain [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (20 sources): abnormal adipose tissue development, abnormal pancreatic beta cell physiology, cardiovascular system phenotype, decreased blood urea nitrogen level, decreased circulating glucose level, decreased epididymal fat pad weight, decreased food intake, decreased insulin secretion, decreased neuron apoptosis, decreased white fat cell size, [+]