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XB-GENEPAGE-5884398
sobp sine oculis binding protein homolog
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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decreased size of the head region (2 sources), decreased size of the otic capsule (2 sources), decreased size of the otic vesicle (2 sources), increased width of neural plate (2 sources), abnormal Meckel's cartilage morphology (1 source), absent otic capsule (1 source), absent palatoquadrate (1 source), decreased size of the branchial arch (1 source), decreased size of the eye (1 source) |
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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Manual annotations: sobp manipulated (13 sources) |
Computed annotations: sobp assayed (1 source) |
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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Xla Wt + sobp (6 sources), Xla Wt + sobp CRISPR (6 sources), Xla Wt + sobpR651X (3 sources), Xla Wt + sobp MO (2 sources) |
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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Human (13 sources): Amblyopia, Delayed speech and language development, Esotropia, Global developmental delay, Hypermetropia, Intellectual disability, severe, Open bite, Poor speech, Psychosis, Short attention span, [+] |
Mouse (9 sources): abnormal cochlea morphology, abnormal motor capabilities/coordination/movement, absent distortion product otoacoustic emissions, absent linear vestibular evoked potential, bidirectional circling, circling, decreased threshold for auditory brainstem response, increased or absent threshold for auditory brainstem response, short scala media |
View all ortholog results at Monarch |