| Monarch Ortholog Phenotypes
|
Human (47 sources):
Abdominal pain,
Abnormality of the hypothalamus-pituitary axis,
Amenorrhea,
Arrhythmia,
Arthralgia,
Arthropathy,
Ascites,
Azoospermia,
Cardiomegaly,
Cardiomyopathy,
Cholestasis,
Chondrocalcinosis,
Chronic pulmonary obstruction,
Cirrhosis,
Congestive heart failure,
Diabetes mellitus,
Dyspnea,
Elevated hepatic transaminase,
Emphysema,
Exocrine pancreatic insufficiency,
Fatigue,
Glucose intolerance,
Gynecomastia,
Hepatic failure,
Hepatic steatosis,
Hepatitis,
Hepatocellular carcinoma,
Hepatomegaly,
Hyperpigmentation of the skin,
Hypogonadism,
Hypogonadotropic hypogonadism,
Impotence,
Increased circulating ferritin concentration,
Increased serum iron,
Jaundice,
Joint dislocation,
Limitation of joint mobility,
Nephrotic syndrome,
Osteoporosis,
Peripheral neuropathy,
Pleural effusion,
Retinopathy,
Splenomegaly,
Telangiectasia,
Testicular atrophy,
Vertigo,
obsolete Hypotrichosis
[+]
|
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Mouse (3 sources):
embryonic lethality, complete penetrance,
no abnormal phenotype detected,
preweaning lethality, complete penetrance
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.