| Monarch Ortholog Phenotypes
|
Human (21 sources):
Absence of the sacrum,
Aortic valve stenosis,
Atrial septal defect,
Bifid uvula,
Butterfly vertebrae,
Cleft palate,
Global developmental delay,
Hypoplastic left heart,
Hypoplastic sacrum,
Intellectual disability,
Laryngeal web,
Laryngotracheomalacia,
Microcephaly,
Mitral stenosis,
Renal hypoplasia,
Sensorineural hearing impairment,
Short stature,
Spinal dysraphism,
Talipes equinovarus,
Tethered cord,
Vesicoureteral reflux
[+]
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|
Mouse (9 sources):
abnormal depression-related behavior,
abnormal embryo development,
abnormal locomotor activation,
abnormal seminal vesicle morphology,
behavior/neurological phenotype,
decreased fasting circulating glucose level,
increased exploration in new environment,
maternal effect,
small kidney
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.