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Summary Expression Phenotypes Gene Literature (284) GO Terms (5) Nucleotides (2533) Proteins (47) Interactants (802) Wiki

prss1     serine protease 1

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: prss1 assayed (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (40 sources): Abdominal pain, Abnormal enzyme/coenzyme activity, Abnormal pancreatic duct morphology, Abnormal thrombosis, Abnormality of circulating enzyme level, Anorexia, Ascites, Biliary hyperplasia, Biliary tract obstruction, Cholelithiasis, [+]
Mouse (6 sources): abnormal pancreatic acinar cell morphology, abnormal pancreatic acinar cell physiology, abnormal seminal vesicle morphology, decreased circulating bilirubin level, increased susceptibility to induced pancreatitis, pancreas necrosis

View all ortholog results at Monarch