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Summary Expression Phenotypes Gene Literature (11) GO Terms (3) Nucleotides (221) Proteins (53) Interactants (282) Wiki
XB-GENEPAGE-5732598

mcrs1     microspherule protein 1

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
decreased apoptosis in neural plate border (1 source), decreased size of the otic vesicle (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: mcrs1 manipulated (71 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + mcrs1 MO (25 sources), Xla Wt + mcrs1 (23 sources), Xla Wt + mcrs1 + six1 MO (6 sources), Xla Wt + six1 + mcrs1 (6 sources), Xla Wt + six1 MO + mcrs1 MO (6 sources), Xla Wt + mcrs1 MO (4 sources), Xla Wt + mcrs1 + six1 MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (10 sources): abnormal embryo size, absent inner cell mass proliferation, decreased embryonic epiblast cell proliferation, embryonic lethality between implantation and somite formation, complete penetrance, embryonic lethality prior to organogenesis, embryonic lethality, complete penetrance, increased mean corpuscular hemoglobin concentration, increased prepulse inhibition, no abnormal phenotype detected, preweaning lethality, complete penetrance