Monarch Ortholog Phenotypes
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Human (22 sources):
Abnormal fundus morphology,
Abnormal visual accommodation,
Abnormality of refraction,
Choroidal melanoma,
Ciliary body melanoma,
Cutaneous melanoma,
Inferior lens subluxation,
Inflammatory abnormality of the eye,
Iris melanoma,
Lung adenocarcinoma,
Meningioma,
Metamorphopsia,
Mydriasis,
Ocular hypertension,
Ocular pain,
Photopsia,
Renal cell carcinoma,
Retinal detachment,
Uveal melanoma,
Visual loss,
Vitreous hemorrhage,
Zonular cataract
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Mouse (38 sources):
abnormal DNA methylation,
abnormal bone marrow cell physiology,
abnormal cardiac thrombosis,
abnormal chorion morphology,
abnormal circulating alkaline phosphatase level,
abnormal epigenetic regulation of gene expression,
abnormal erythropoiesis,
abnormal hematopoietic stem cell physiology,
abnormal hematopoietic system morphology/development,
abnormal myelopoiesis,
abnormal placenta morphology,
abnormal trophoblast layer morphology,
abnormal vibrissa morphology,
abnormal visceral yolk sac morphology,
abnormal vocalization,
cardiac muscle necrosis,
embryonic growth retardation,
embryonic lethality between implantation and placentation, complete penetrance,
embryonic lethality during organogenesis, complete penetrance,
embryonic lethality during organogenesis, incomplete penetrance,
heart inflammation,
hematopoietic system phenotype,
increased circulating alkaline phosphatase level,
increased colon tumor incidence,
increased granulosa cell tumor incidence,
increased hematopoietic stem cell number,
increased incidence of tumors by chemical induction,
increased lung carcinoma incidence,
increased lymphoma incidence,
increased mammary adenocarcinoma incidence,
increased mesothelioma incidence,
increased neutrophil cell number,
increased nucleated erythrocyte cell number,
increased pancreatic islet cell carcinoma incidence,
increased skin tumor incidence,
lethality throughout fetal growth and development, complete penetrance,
myeloid hyperplasia,
preweaning lethality, complete penetrance
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View all ortholog results at Monarch
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