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XB-GENEPAGE-494816
smarca5 SNF2 related chromatin remodeling ATPase 5
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal lens (2 sources), abnormal retina morphology (2 sources), decreased size of the lens fiber cell mass (2 sources), abnormal anterior-posterior axis (1 source), abnormal brain morphology (1 source), abnormal cornea morphology (1 source), abnormal eye morphology (1 source), abnormal foregut morphology (1 source), abnormal head (1 source), abnormal hindgut morphology (1 source), abnormally increased number of retinal ganglion cell (1 source), abnormal midgut morphology (1 source), abnormal neural tube closure (1 source), abnormal retinal pigmented epithelium morphology (1 source), abnormal spinal cord (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: smarca5 manipulated (1 source) |
| Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes
from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
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| cataract (2AP sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + smarca5 MO (4 sources), Xla Wt + smarca5 (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Mouse (9 sources): abnormal embryo development, abnormal inner cell mass apoptosis, absent inner cell mass proliferation, embryonic growth arrest, embryonic lethality between implantation and somite formation, complete penetrance, increased trophectoderm apoptosis, inner cell mass degeneration, preweaning lethality, complete penetrance, trophectoderm cell degeneration |