Delayed speech and language development, Dysarthria, Dyskinesia, Dysplastic corpus callosum, Dystonia, EEG abnormality, Epileptic encephalopathy, Feeding difficulties, Flexion contracture, Frontal bossing, Generalized hypotonia, Global developmental delay, Hyperkinetic movements, Hyperreflexia, Hypoplasia of the corpus callosum, Inability to walk, Intellectual disability, Intellectual disability, moderate, Intellectual disability, severe, Involuntary movements, Lissencephaly, Microcephaly, Microphthalmia, Midface retrusion, Mild short stature, Myoclonus, Narrow mouth, Oculogyric crisis, Optic nerve hypoplasia, Polymicrogyria, Poor eye contact, Poor speech, Scoliosis, Seizure, Self-injurious behavior, Severe muscular hypotonia, Short stature, Spasticity, Strabismus, Thin ribs

abnormal discrimination learning, abnormal excitatory postsynaptic currents, abnormal food intake, abnormal glutamate-mediated receptor currents, abnormal hearing electrophysiology, abnormal liquid preference, abnormal locomotor behavior, abnormal long term potentiation, abnormal maternal grooming, abnormal maternal nurturing, abnormal medium spiny neuron morphology, abnormal miniature excitatory postsynaptic currents, abnormal motor capabilities/coordination/movement, abnormal motor learning, abnormal nest building behavior, abnormal neuron physiology, abnormal object recognition memory, abnormal olfactory discrimination memory, abnormal physiological response to xenobiotic, abnormal postnatal growth, abnormal postural reflex, abnormal primary somatosensory cortex morphology, abnormal pulmonary respiratory rate, abnormal pup retrieval, abnormal sexual interaction, abnormal single cell response, abnormal social investigation, abnormal somatosensory cortex morphology, abnormal spatial learning, abnormal spatial working memory, abnormal suckling behavior, absence of NMDA-mediated synaptic currents, absent barrels in primary somatosensory cortex, absent gastric milk in neonates, absent long term depression, absent suckling reflex, aphagia, behavior/neurological phenotype, cardiovascular system phenotype, decreased aggression towards mice, decreased alcohol consumption, decreased circulating alkaline phosphatase level, decreased excitatory postsynaptic current amplitude, decreased locomotor activity, decreased prepulse inhibition, decreased susceptibility to neuronal excitotoxicity, decreased susceptibility to pharmacologically induced seizures, decreased vertical activity, decreased vocalization, growth/size/body region phenotype, hearing/vestibular/ear phenotype, homeostasis/metabolism phenotype, impaired behavioral response to cocaine, impaired conditioned place preference behavior, impaired passive avoidance behavior, impaired righting response, impaired social transmission of food preference, impaired synaptic plasticity, increased alcohol consumption, increased anxiety-related response, increased exploration in new environment, increased grooming behavior, increased startle reflex, increased susceptibility to pharmacologically induced seizures, increased thigmotaxis, limb grasping, lung hemorrhage, neonatal lethality, complete penetrance, nervous system phenotype, no abnormal phenotype detected, obsolete abnormal mouse huddling behavior, overexpanded pulmonary alveoli, perinatal lethality, complete penetrance, perinatal lethality, incomplete penetrance, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, premature death, pup cannibalization, reduced AMPA-mediated synaptic currents, reduced NMDA receptor mediated synaptic activity in barrel cortex, reduced NMDA-mediated synaptic currents, reduced long term potentiation, reduced male fertility, reduced male mating frequency, reproductive system phenotype, social withdrawal, taste/olfaction phenotype, vision/eye phenotype