lhx6 Phenotypes

Phenotypes

XB-GENEPAGE-493340

Gene Symbol: lhx6 Gene Name: LIM homeobox 6

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: lhx6 assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (19 sources): abnormal adipose tissue amount, abnormal brain interneuron morphology, abnormal cerebral cortex morphology, abnormal inhibitory postsynaptic currents, abnormal locomotor activation, abnormal miniature inhibitory postsynaptic currents, abnormal neuron differentiation, abnormal spike wave discharge, decreased locomotor activity, decreased neuron number, decreased vertical activity, environmentally induced seizures, increased susceptibility to pharmacologically induced seizures, increased total body fat amount, nervous system phenotype, no abnormal phenotype detected, postnatal lethality, complete penetrance, preweaning lethality, incomplete penetrance, weakness [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (19 sources): abnormal adipose tissue amount, abnormal brain interneuron morphology, abnormal cerebral cortex morphology, abnormal inhibitory postsynaptic currents, abnormal locomotor activation, abnormal miniature inhibitory postsynaptic currents, abnormal neuron differentiation, abnormal spike wave discharge, decreased locomotor activity, decreased neuron number, [+]