msx1 Phenotypes

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Phenotypes

Gene Literature (205)

Nucleotides (277)

Interactants (1265)

XB-GENEPAGE-490377

Gene Symbol: msx1 Gene Name: msh homeobox 1

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal tail morphology (2 sources), abnormal bending of tail (1 source), abnormal development of neural crest (1 source), abnormal swimming behavior (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: msx1 manipulated (12 sources), msx1 assayed (24 sources)
Computed annotations: msx1 assayed (15 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + msx1 (6 sources), Xla Wt + msx1 MO (5 sources), Xtr Wt + msx1 MO (3 sources), Xla Wt + hmga2 + msx1 (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (29 sources): Abnormal fingernail morphology, Abnormality of dental morphology, Abnormality of the dentition, Abnormality of the face, Abnormality of the nail, Agenesis of permanent teeth, Cleft palate, Cleft upper lip, Concave nail, Conical tooth, Delayed eruption of teeth, Everted lower lip vermilion, Fine hair, Fragile nails, Hypodontia, Hypoplasia of the maxilla, Hypoplastic fingernail, Hypoplastic toenails, Microdontia, Microdontia of primary teeth, Micrognathia, Nail pits, Oligodontia, Polycystic ovaries, Ridged fingernail, Ridged nail, Small nail, Sparse hair, Thin toenail [+]
Mouse (38 sources): abnormal brain commissure morphology, abnormal breathing pattern, abnormal cranium morphology, abnormal diencephalon morphology, abnormal embryo size, abnormal embryonic tissue morphology, abnormal epitympanic recess morphology, abnormal frontal bone morphology, abnormal liver development, abnormal mandible morphology, abnormal metopic suture morphology, abnormal palatal shelf fusion at midline, abnormal palate morphology, abnormal roof plate morphology, abnormal subcommissural organ morphology, absent alveolar process, absent gastric milk in neonates, absent lower incisors, absent malleus processus brevis, absent maxillary shelf, absent palatine bone horizontal plate, absent upper incisors, cardiovascular system phenotype, decreased thigmotaxis, growth retardation of molars, increased neuron number, limb grasping, limbs/digits/tail phenotype, neonatal lethality, complete penetrance, no abnormal phenotype detected, overlapping parietal bones, palatal shelf hypoplasia, preweaning lethality, complete penetrance, short malleus, short mandible, short maxilla, small nasal bone, thoracoabdominoschisis [+]
View all ortholog results at Monarch