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Summary Expression Phenotypes Gene Literature (32) GO Terms (1) Nucleotides (68) Proteins (38) Interactants (259) Wiki

nphs1     NPHS1 nephrin

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: nphs1 assayed (4 sources)
Computed annotations: nphs1 assayed (2 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (22 sources): Abdominal distention, Abnormal renal tubule morphology, Congenital nephrotic syndrome, Delayed eruption of permanent teeth, Diffuse mesangial sclerosis, Edema, Elevated amniotic fluid alpha-fetoprotein, Gastroesophageal reflux, Glomerular sclerosis, Growth delay, [+]
Mouse (22 sources): abnormal kidney morphology, abnormal podocyte foot process morphology, abnormal podocyte slit diaphragm morphology, abnormal podocyte slit junction morphology, abnormal renal glomerulus morphology, abnormal renal reabsorption, absent podocyte slit diaphragm, dilated distal convoluted tubule, dilated proximal convoluted tubule, dilated renal glomerular capsule, [+]

View all ortholog results at Monarch