Monarch Ortholog Phenotypes
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Mouse (38 sources):
abnormal anterior visceral endoderm cell migration,
abnormal cardiac neural crest cell migration,
abnormal cell proliferation,
abnormal common carotid artery morphology,
abnormal cranium morphology,
abnormal developmental patterning,
abnormal dorsal spinal root morphology,
abnormal embryonic epiblast morphology,
abnormal enteric neural crest cell migration,
abnormal extraembryonic endoderm formation,
abnormal heart development,
abnormal placenta labyrinth morphology,
abnormal proximal-distal axis patterning,
abnormal spinal nerve morphology,
abnormal trophoblast layer morphology,
absent frontal bone,
absent mesoderm,
absent nasal capsule,
absent spongiotrophoblast,
decreased embryonic epiblast cell proliferation,
embryonic lethality, complete penetrance,
eyelids open at birth,
failure of primitive streak formation,
failure to gastrulate,
increased apoptosis,
increased hindbrain apoptosis,
mandibular hyperostosis,
perinatal lethality, complete penetrance,
prenatal lethality, complete penetrance,
short mandible,
short maxilla,
short premaxilla,
small basioccipital bone,
small dorsal root ganglion,
small embryonic epiblast,
small interparietal bone,
small parietal bone,
small pharyngeal arch
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