socs2 Phenotypes

Phenotypes

XB-GENEPAGE-487260

Gene Symbol: socs2 Gene Name: suppressor of cytokine signaling 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: socs2 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (37 sources): abnormal circulating cytokine level, abnormal fertility/fecundity, abnormal hepatobiliary system morphology, abnormal insulin-like growth factor I level, abnormal long bone epiphyseal plate proliferative zone, abnormal macrophage physiology, abnormal pancreatic duct morphology, abnormal salivary gland duct morphology, adipose tissue phenotype, decreased bone trabecular spacing, decreased circulating growth hormone level, decreased circulating insulin-like growth factor I level, decreased energy expenditure, decreased liver triglyceride level, decreased susceptibility to hepatic steatosis, increased body length, increased bone trabecula number, increased circulating glucose level, increased circulating interferon-gamma level, increased circulating interleukin-1 beta level, increased compact bone area, increased diameter of tibia, increased growth rate, increased interferon-gamma secretion, increased interleukin-1 beta secretion, increased length of long bones, increased long bone epiphyseal plate size, increased renal fat pad weight, increased trabecular bone thickness, increased trabecular bone volume, increased triglyceride level, increased tumor necrosis factor secretion, increased width of hypertrophic chondrocyte zone, long femur, long humerus, skeleton phenotype, thick dermal layer [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (37 sources): abnormal circulating cytokine level, abnormal fertility/fecundity, abnormal hepatobiliary system morphology, abnormal insulin-like growth factor I level, abnormal long bone epiphyseal plate proliferative zone, abnormal macrophage physiology, abnormal pancreatic duct morphology, abnormal salivary gland duct morphology, adipose tissue phenotype, decreased bone trabecular spacing, [+]