abnormal lipid homeostasis, abnormal liver development, abnormal nucleotide metabolism, abnormal physiological neovascularization, abnormal red blood cell distribution width, abnormal response to injury, abnormal retina blood vessel morphology, abnormal sinus arrhythmia, abnormal small intestine goblet cell morphology, abnormal white adipose tissue morphology, absent Paneth cells, absent trabeculae carneae, anoxia, behavior/neurological phenotype, crypts of Lieberkuhn abscesses, decreased IgG1 level, decreased Paneth cell number, decreased angiogenesis, decreased body fat mass, decreased brown adipose tissue mass, decreased cell proliferation, decreased cholesterol level, decreased embryo size, decreased embryo weight, decreased fat cell size, decreased fatty acids level, decreased hepatocyte proliferation, decreased red blood cell distribution width, decreased small intestinal villus size, decreased susceptibility to diet-induced obesity, decreased susceptibility to prion infection, decreased white adipose tissue mass, embryo tissue necrosis, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, enlarged pericardium, impaired hematopoiesis, increased apoptosis, increased basal metabolism, increased body fat mass, increased carbon dioxide production, increased fatty acid oxidation, increased grip strength, increased hepatocyte apoptosis, increased oxygen consumption, increased susceptibility to induced colitis, increased total body fat amount, intestinal ulcer, liver hypoplasia, nervous system phenotype, preweaning lethality, complete penetrance, small intestinal inflammation, small liver, thin ventricular wall, wavy neural tube