fgf2 Phenotypes

Phenotypes

XB-GENEPAGE-487001

Gene Symbol: fgf2 Gene Name: fibroblast growth factor 2

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
increased cell population proliferation in optic tectum (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: fgf2 manipulated (5 sources)
Computed annotations: fgf2 assayed (3 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + fgf2 + animal cap explant (3 sources), Xla Wt + fgf2 MO (2 sources), Xla Wt + fgf2 + animal cap explant (1 source), Xla Wt + Hsa.FGF2 + animal cap explant (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (35 sources): abnormal baroreceptor physiology, abnormal bone marrow morphology, abnormal cardiac muscle relaxation, abnormal cerebral cortex morphology, abnormal cerebral cortex pyramidal cell morphology, abnormal common myeloid progenitor cell morphology, abnormal frontal lobe morphology, abnormal hippocampal commissure morphology, abnormal myeloblast morphology/development, abnormal neuron differentiation, abnormal response to cardiac infarction, abnormal sleep pattern, abnormal spinal cord grey matter morphology, abnormal stratification in cerebral cortex, abnormal vascular endothelial cell migration, behavior/neurological phenotype, cardiovascular system phenotype, decreased bone mineral content, decreased cardiac muscle contractility, decreased cerebral cortex pyramidal cell number, decreased left ventricle developed pressure, decreased left ventricle systolic pressure, decreased mean systemic arterial blood pressure, decreased vasoconstriction, delayed wound healing, hearing/vestibular/ear phenotype, increased cardiomyocyte apoptosis, increased myocardial infarct size, limb grasping, loss of cortex neurons, loss of glutamate neurons, muscle phenotype, reproductive system phenotype, thin cerebral cortex, vision/eye phenotype [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (35 sources): abnormal baroreceptor physiology, abnormal bone marrow morphology, abnormal cardiac muscle relaxation, abnormal cerebral cortex morphology, abnormal cerebral cortex pyramidal cell morphology, abnormal common myeloid progenitor cell morphology, abnormal frontal lobe morphology, abnormal hippocampal commissure morphology, abnormal myeloblast morphology/development, abnormal neuron differentiation, [+]