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Summary Expression Phenotypes Gene Literature (90) GO Terms (6) Nucleotides (107) Proteins (63) Interactants (568) Wiki

tbx5     T-box 5

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
absent blood in the heart (1 source), absent lung bud (1 source), edematous embryo (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: tbx5 manipulated (2 sources), tbx5 assayed (1 source)
Computed annotations: tbx5 assayed (7 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + tbx5 CRISPR (3 sources), Xtr Wt + tbx5 MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (46 sources): Abnormal aortic morphology, Abnormal carpal morphology, Abnormal clavicle morphology, Abnormal rib morphology, Abnormal vertebral morphology, Abnormality of cardiovascular system morphology, Abnormality of the humerus, Abnormality of the metacarpal bones, Absent radius, Absent thumb, [+]
Mouse (36 sources): abnormal abdominal wall morphology, abnormal atrioventricular bundle conduction, abnormal atrioventricular bundle morphology, abnormal atrioventricular node conduction, abnormal forelimb bud morphology, abnormal forelimb morphology, abnormal heart development, abnormal heart tube morphology, abnormal impulse conducting system conduction, abnormal impulse conducting system morphology, [+]

View all ortholog results at Monarch