| Monarch Ortholog Phenotypes
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Human (26 sources):
Abnormal hair morphology,
Abnormal lacrimal duct morphology,
Abnormality of the breast,
Abnormality of the menstrual cycle,
Amenorrhea,
Blepharophimosis,
Cupped ear,
Depressed nasal bridge,
Epicanthus,
Epicanthus inversus,
Female infertility,
High palate,
Hypermetropia,
Hypoplasia of the uterus,
Increased circulating gonadotropin level,
Microcornea,
Microphthalmia,
Myopia,
Nystagmus,
Premature ovarian insufficiency,
Ptosis,
Secondary amenorrhea,
Strabismus,
Synophrys,
Telecanthus,
Wide nasal bridge
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Mouse (13 sources):
abnormal ovarian follicle morphology,
abnormal ovary size,
absent mature ovarian follicles,
decreased circulating insulin-like growth factor I level,
eyelids open at birth,
impaired ovarian folliculogenesis,
no abnormal phenotype detected,
postnatal lethality,
postnatal lethality, incomplete penetrance,
primary sex reversal,
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.