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XB-GENEPAGE-486594
wnt2 Wnt family member 2
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal development of lung (2 sources) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: wnt2 manipulated (8 sources), wnt2 assayed (2 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + Mmu.fgfr1del-Mmu.fkbp1adel + wnt2 MO + B/B Homodimerizer (3 sources), Xla Wt + wnt2 MO (3 sources), Xla Wt + Mmu.lef1-Mmu.ctnnb1-GR + wnt2 MO + DEX (2 sources) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Mouse (11 sources): abnormal fetal growth/weight/body size, abnormal lung vasculature morphology, abnormal lung-associated mesenchyme development, abnormal placenta development, abnormal placenta labyrinth morphology, abnormal placenta morphology, abnormal placenta vasculature, decreased body size, decreased mesenchymal cell proliferation involved in lung development, neonatal lethality, incomplete penetrance, [+] |