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XB-GENEPAGE-486198
pias4 protein inhibitor of activated STAT 4
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal bending of anterior-posterior axis (4 sources), abnormal head morphology (4 sources), abnormally ventralized embryo (2 sources), absent head (2 sources), absent cement gland (1 source), decreased length of anterior-posterior axis (1 source), increased size of the endoderm (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: pias4 manipulated (1 source), pias4 assayed (3 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + pias4 (4 sources), Xla Wt + ctnnb1 + pias4 (1 source), Xla Wt + ctnnb1 + pias4 (1 source), Xla Wt + pias4 (1 source), Xla Wt + pias4 + smad2 + animal cap explant (1 source), Xla Wt + pias4del (1 source), Xla Wt + pias4del (1 source), Xla Wt + pias4del (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Mouse (4 sources): abnormal myelopoiesis, no abnormal phenotype detected, perinatal lethality, incomplete penetrance, postnatal lethality |