| Monarch Ortholog Phenotypes
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Human (5 sources):
Congenital corneal dystrophy,
Glaucoma,
Increased corneal thickness,
Progressive visual loss,
Strabismus
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Mouse (24 sources):
abnormal cornea posterior stroma morphology,
abnormal corneal stroma morphology,
abnormal cutaneous collagen fibril morphology,
abnormal humoral immune response,
abnormal periodontal ligament morphology,
abnormal renal tubule epithelium morphology,
behavior/neurological phenotype,
decreased body length,
decreased skin tensile strength,
decreased susceptibility to bacterial infection,
dilated renal tubules,
hematopoietic system phenotype,
homeostasis/metabolism phenotype,
immune system phenotype,
increased glomerular capsule space,
increased renal tubule apoptosis,
no abnormal phenotype detected,
periodontal ligament hypercellularity,
reduced female fertility,
salivary gland epithelial hyperplasia,
skeleton phenotype,
thin dermal layer,
tubular nephritis,
vision/eye phenotype
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.