prox1 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-485326

Gene Symbol: prox1 Gene Name: prospero homeobox 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: prox1 assayed (1 source)
Computed annotations: prox1 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (42 sources): abnormal atrial thrombosis, abnormal cardiac thrombosis, abnormal dentate gyrus morphology, abnormal endocrine pancreas morphology, abnormal eye development, abnormal hippocampus CA4 region morphology, abnormal hippocampus granule cell morphology, abnormal interventricular septum muscular part morphology, abnormal lens development, abnormal liver development, abnormal lymph circulation, abnormal lymph organ development, abnormal myocardial fiber morphology, abnormal skeletal muscle morphology, abnormal suckling behavior, abnormal ventricular thrombosis, absent retina horizontal cells, cardiovascular system phenotype, decreased cardiac muscle contractility, decreased hepatocyte proliferation, decreased locomotor activity, decreased lymphatic vessel endothelial cell number, decreased survivor rate, dilated heart, increased circulating alanine transaminase level, increased liver triglyceride level, increased macrophage cell number, increased pancreatic acinar cell number, increased susceptibility to age related obesity, increased total body fat amount, increased total fat pad weight, increased total retina thickness, interventricular septum membranous part aneurysm, lethality throughout fetal growth and development, complete penetrance, no abnormal phenotype detected, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, premature death, small liver, small pancreas, thick tricuspid valve cusps, thin myocardium [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (42 sources): abnormal atrial thrombosis, abnormal cardiac thrombosis, abnormal dentate gyrus morphology, abnormal endocrine pancreas morphology, abnormal eye development, abnormal hippocampus CA4 region morphology, abnormal hippocampus granule cell morphology, abnormal interventricular septum muscular part morphology, abnormal lens development, abnormal liver development, [+]