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Summary Expression Phenotypes Gene Literature (32) GO Terms (35) Nucleotides (64) Proteins (36) Interactants (301) Wiki

fgf10     fibroblast growth factor 10

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal digit-joint region (1 source), abnormal digit-joint region morphology in the regenerating forelimb (1 source), abnormal forelimb digit (1 source), abnormal regenerating forelimb (1 source), abnormal regenerating forelimb morphology (1 source), abnormally decreased number of digit-joint region in the regenerating forelimb (1 source), increased branchiness of regenerating forelimb (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: fgf10 assayed (1 source)
Computed annotations: fgf10 assayed (7 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + Hsa.FGF10 + Hsa.SHH + TMSB4X + forelimb amputation (2 sources), Xla Wt + Hsa.FGF10 + Hsa.SHH + forelimb amputation (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (42 sources): 2-3 finger syndactyly, Absence of Stensen duct, Absent lacrimal punctum, Absent proximal phalanx of thumb, Absent radius, Alacrima, Aplasia of the parotid gland, Bilateral triphalangeal thumbs, Broad forehead, Broad hallux, [+]
Mouse (110 sources): Harderian gland atrophy, abnormal Rathke's pouch apoptosis, abnormal Wolffian duct morphology, abnormal branching involved in trachea morphogenesis, abnormal branching of the mammary ductal tree, abnormal cecum development, abnormal cochlea morphology, abnormal colon morphology, abnormal crista ampullaris morphology, abnormal ear morphology, [+]

View all ortholog results at Monarch