klf2 Phenotypes

Phenotypes

XB-GENEPAGE-485034

Gene Symbol: klf2 Gene Name: KLF transcription factor 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: klf2 assayed (10 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (29 sources): abnormal T cell differentiation, abnormal aorta tunica media morphology, abnormal embryonic tissue morphology, abnormal epicardium morphology, abnormal mandible morphology, abnormal vascular endothelial cell morphology, abnormal vascular smooth muscle morphology, absent T cells, absent heartbeat, decreased Ly6C low monocyte number, decreased embryo size, decreased systemic vascular resistance, embryo tissue necrosis, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, immune system phenotype, impaired hematopoiesis, increased IgG1 level, increased cardiac output, increased cardiac stroke volume, increased interleukin-4 secretion, increased nucleated erythrocyte cell number, increased single-positive T cell number, lethality throughout fetal growth and development, complete penetrance, no abnormal phenotype detected, pale liver, pale yolk sac, prenatal lethality, complete penetrance, thin myocardium [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (29 sources): abnormal T cell differentiation, abnormal aorta tunica media morphology, abnormal embryonic tissue morphology, abnormal epicardium morphology, abnormal mandible morphology, abnormal vascular endothelial cell morphology, abnormal vascular smooth muscle morphology, absent T cells, absent heartbeat, decreased Ly6C low monocyte number, [+]