gata5 Phenotypes

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Phenotypes

Gene Literature (49)

Nucleotides (153)

Interactants (707)

XB-GENEPAGE-484905

Gene Symbol: gata5 Gene Name: GATA binding protein 5

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: gata5 manipulated (1 source), gata5 assayed (10 sources)
Computed annotations: gata5 assayed (18 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla.Tg(myl2:GFP)Mohun + gata5 MO + Activin + explant (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (29 sources): Abnormal left ventricular outflow tract morphology, Abnormal nasal morphology, Aortic arch aneurysm, Aortic regurgitation, Aortic valve calcification, Aortic valve stenosis, Ascending aortic dissection, Atrial fibrillation, Atrial septal defect, Bicuspid aortic valve, Brachydactyly, Broad forehead, Clinodactyly of the 5th finger, Coarctation of aorta, Cryptorchidism, Dilated cardiomyopathy, Dolichocephaly, Double outlet right ventricle, Heart murmur, Hypertension, Hypoplastic left heart, Intrauterine growth retardation, Preauricular pit, Proptosis, Tetralogy of Fallot, Thin vermilion border, Thoracic aorta calcification, Underdeveloped supraorbital ridges, Ventricular septal defect [+]
Mouse (35 sources): abnormal aorta bulb morphology, abnormal female reproductive system morphology, abnormal female urethra morphology, abnormal fetal cardiomyocyte morphology, abnormal heart development, abnormal kidney morphology, abnormal perineum morphology, abnormal renal glomerulus morphology, abnormal renal/urinary system morphology, abnormal seminal vesicle morphology, abnormal urethra urothelium morphology, abnormal vagina epithelium morphology, abnormal vagina morphology, abnormal vagina orifice morphology, abnormal vasodilation, absent clitoral bone, behavior/neurological phenotype, cardiovascular system phenotype, decreased myocardial fiber number, decreased renal glomerular filtration rate, decreased renin activity, enlarged myocardial fiber, female preputial gland hypoplasia, increased left ventricle weight, increased systemic arterial diastolic blood pressure, increased systemic arterial systolic blood pressure, increased ventricle muscle contractility, myocardial trabeculae hypoplasia, perivascular fibrosis, reduced female fertility, salt-sensitive hypertension, short perineum, thick interventricular septum, thin ventricular wall, urethritis [+]
View all ortholog results at Monarch