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Summary Expression Phenotypes Gene Literature (117) GO Terms (12) Nucleotides (141) Proteins (57) Interactants (613) Wiki

gli3     GLI family zinc finger 3

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal development of transient tracheoesophageal septum (1 source), abnormal tracheoesophageal fold morphology (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: gli3 manipulated (2 sources)
Computed annotations: gli3 assayed (6 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + gli2 MO + gli3 MO (1 source), Xla Wt + gli3 MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (219 sources): 1-3 toe syndactyly, 1-5 toe syndactyly, 3-4 finger cutaneous syndactyly, 3-4 finger syndactyly, Abnormal basal ganglia MRI signal intensity, Abnormal cardiac septum morphology, Abnormal cardiovascular system morphology, Abnormal clavicle morphology, Abnormal corpus callosum morphology, Abnormal earlobe morphology, [+]
Mouse (151 sources): Harderian gland hyperplasia, abnormal anterior cardinal vein morphology, abnormal basisphenoid bone morphology, abnormal bone mineralization, abnormal cerebellar Purkinje cell layer, abnormal cerebellar foliation, abnormal cerebral aqueduct morphology, abnormal cerebral cortex morphology, abnormal cerebral hemisphere morphology, abnormal choroid plexus morphology, [+]

View all ortholog results at Monarch