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Summary Expression Phenotypes Gene Literature (372) GO Terms (0) Nucleotides (1242) Proteins (107) Interactants (1787) Wiki

fn1     fibronectin 1

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal cell adhesion (3 sources), decreased cell adhesion in mesodermal cell (3 sources), abnormal incomplete closing of the neural tube (1 source), abnormal pathway-restricted SMAD protein phosphorylation (1 source), abnormally split primary heart field (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: fn1 manipulated (7 sources), fn1 assayed (10 sources)
Computed annotations: fn1 assayed (9 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + fn1 MO + sdc4 MO (3 sources), Xla Wt + fn1 MO (2 sources), Xla Wt + fn1 MO (2 sources), Xla Wt + KD-Pak1 + fn1 MO (2 sources), Xla Wt + KD-Pak1 + fn1 MO + cdh3 MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (65 sources): abnormal amnion morphology, abnormal atrioventricular cushion morphology, abnormal cardiac jelly morphology, abnormal cardiac outflow tract development, abnormal developmental patterning, abnormal dorsal aorta morphology, abnormal embryonic neuroepithelium morphology, abnormal embryonic tissue morphology, abnormal endocardium morphology, abnormal extracellular matrix morphology, [+]