abnormal circulating interleukin-4 level, abnormal circulating interleukin-5 level, abnormal class switch recombination, abnormal cytotoxic T cell physiology, abnormal granulocyte physiology, abnormal humoral immune response, abnormal leukocyte migration, abnormal leukocyte physiology, abnormal level of surface class II molecules, abnormal macrophage physiology, abnormal mammary gland epithelium morphology, abnormal mammary gland growth during pregnancy, abnormal mammary gland morphology, abnormal noradrenaline level, abnormal renal tubule morphology, abnormal tumor susceptibility, acanthosis, decreased B cell proliferation, decreased IgG1 level, decreased IgG3 level, decreased T cell proliferation, decreased T-helper 2 cell number, decreased core body temperature, decreased fatty acids level, decreased interleukin-4 secretion, decreased interleukin-5 secretion, decreased mammary gland epithelial cell proliferation, decreased metastatic potential, decreased susceptibility to Herpesvirales infection, decreased susceptibility to autoimmune diabetes, immune system phenotype, impaired eosinophil chemotaxis, impaired eosinophil recruitment, increased B cell apoptosis, increased IgG1 level, increased IgG2a level, increased cellular sensitivity to gamma-irradiation, increased circulating creatine level, increased circulating tumor necrosis factor level, increased interferon-gamma secretion, increased interleukin-12 secretion, increased interleukin-2 secretion, increased susceptibility to parasitic infection, liver/biliary system phenotype, skin lesions