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XB-GENEPAGE-483692
pax8 paired box 8
Anatomical Phenotypes
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abnormal pronephric kidney morphology (3 sources), abnormal development of pronephric kidney (2 sources), abnormal proximal tubule morphology (1 source), absent pronephric tubule (1 source), absent proximal tubule (1 source), edematous ventral trunk (1 source) |
Expression Phenotypes
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Manual annotations: pax8 manipulated (11 sources), pax8 assayed (8 sources) |
Computed annotations: pax8 assayed (11 sources) |
Diseases
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kidney disease (2AP sources, 1 EP source) |
Experiments (Reagents)
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Xla Wt + pax8 MO (10 sources), Xla Wt + pax8 + CHX + DEX + animal cap amputation (1 source), Xla Wt + Tg(Xtr.pax8:GFP)del_CNS1/2 (1 source), Xtr Wt + pax8 CRISPR (1 source), Xtr Wt + pax8 MO (1 source), Xtr Wt + pax8 MO (1 source) |
Monarch Ortholog Phenotypes
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Human (36 sources): Abdominal distention, Abnormality of the face, Abnormality of the thyroid gland, Bradycardia, Coarse facial features, Congenital hypothyroidism, Constipation, Delayed skeletal maturation, Dry skin, Ectopic thyroid, [+] |
Mouse (68 sources): abnormal action potential, abnormal adenohypophysis morphology, abnormal auditory bulla morphology, abnormal bone remodeling, abnormal caput epididymis morphology, abnormal cochlear hair cell morphology, abnormal cochlear hair cell stereociliary bundle morphology, abnormal cochlear IHC efferent innervation pattern, abnormal cochlear inner hair cell physiology, abnormal corpus epididymis morphology, [+] |
View all ortholog results at Monarch |