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Summary Expression Phenotypes Gene Literature (24) GO Terms (3) Nucleotides (145) Proteins (54) Interactants (240) Wiki

bmpr1b     bone morphogenetic protein receptor type 1B

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
increased pigmentation in the head (4 sources), abnormally incomplete structure of head (3 sources), decreased pigmentation in the eye (3 sources), abnormal branchial arch morphology (2 sources), abnormal cartilage element morphology (2 sources), abnormal ceratohyal morphology (2 sources), abnormal ventral tail fin morphology (2 sources), abnormally localised dorsal fin (2 sources), abnormally localised melanophore in dorsal fin (2 sources), absent branchial arch (2 sources), absent cartilage element in the branchial arch (2 sources), absent ceratohyal (2 sources), absent intercanthal region (2 sources), decreased size of the branchial arch (2 sources), decreased width of the cartilage element in head (2 sources), decreased width of the head (2 sources), abnormal cell migration in neural crest (1 source), wholly anteriorized tadpole (1 source), wholly dorsalized embryo (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: bmpr1b manipulated (5 sources)
Computed annotations: bmpr1b assayed (5 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + bmpr1b MO (7 sources), Xla Wt + bmpr1b MO (4 sources), Xla Wt + bmpr1b MO (2 sources), Xla Wt + bmpr1a MO + bmpr1b MO (1 source), Xla Wt + bmpr1b MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (90 sources): 2-3 toe syndactyly, Abnormal hip bone morphology, Abnormal thumb morphology, Abnormality of epiphysis morphology, Abnormality of the radius, Abnormality of the ulna, Abnormality of tibia morphology, Acromesomelia, Aplasia of the fingers, Aplasia of the middle phalanges of the toes, [+]
Mouse (19 sources): abnormal axon guidance, abnormal cartilage development, abnormal chondrocyte differentiation, abnormal digit development, abnormal endometrial gland development, abnormal metacarpal bone morphology, abnormal phalanx morphology, abnormal retina ganglion cell morphology, absent cumulus expansion, absent endometrial glands, [+]

View all ortholog results at Monarch