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XB-GENEPAGE-482919
sfrp5 secreted frizzled-related protein 5
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal foregut epithelium morphology (5 sources), abnormal development of alimentary system (4 sources), abnormal development of foregut (4 sources), abnormal development of hindgut (3 sources), abnormal foregut morphology (2 sources), abnormally decreased coiling of foregut (2 sources), increased size of the foregut (2 sources), increased size of the hindgut (2 sources), abnormal archenteron floor morphology (1 source), abnormal bending of anterior-posterior axis (1 source), abnormal endodermal cell morphology (1 source), abnormal establishment of apical/basal cell polarity (1 source), abnormal gastrulation (1 source), abnormal liver morphology (1 source), abnormal regulation of protein folding (1 source), abnormally decreased length of hindgut (1 source), abnormally localised actin filament (1 source), abnormally localised foregut (1 source), decreased length of anterior-posterior axis (1 source), decreased size of the hindgut (1 source), decreased size of the liver (1 source), decreased size of the ventral pancreatic bud (1 source), increased apoptosis in foregut (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: sfrp5 manipulated (32 sources) |
| Computed annotations: sfrp5 assayed (1 source) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + sfrp5 MO (10 sources), Xla Wt + sfrp5 MO (7 sources), Xla Wt + sfrp5 MO (7 sources), Xla Wt + sfrp5 (5 sources), Xla Wt + sfrp5 MO (3 sources), Xla Wt + sfrp5 (2 sources), Xla Wt + sfrp5 (2 sources), Xla Wt + sfrp5 MO + Go 6850 (2 sources), Xla Wt + sfrp5 MO + NSC 23766 (2 sources), Xla Wt + sfrp5 MO + SP600125 (2 sources), Xla Wt + sfrp5 MO + Y27632 (2 sources), Xla Wt + dndvl2-GFP + sfrp5 MO (2 sources), Xla Wt + dntcf3-GR + sfrp5 MO + DEX (2 sources), Xla Wt + dkk1 + sfrp5 MO (1 source), Xla Wt + sfrp5 (1 source), Xla Wt + sfrp5 + wnt11 (1 source), Xla Wt + sfrp5 + wnt5a (1 source), Xla Wt + sfrp5 + wnt5b (1 source), Xla Wt + sfrp5 + caHsa.MAPK8 (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Mouse (2 sources): no abnormal phenotype detected, reproductive system phenotype |