Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (100) GO Terms (4) Nucleotides (492) Proteins (60) Interactants (506) Wiki

cdh3     cadherin 3

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal cell adhesion (3 sources), abnormal gastrulation (3 sources), decreased cell adhesion in mesodermal cell (3 sources), abnormal animal hemisphere morphology (2 sources), abnormal axial mesoderm morphology (2 sources), abnormal tail morphology (2 sources), decreased length of anterior-posterior axis (2 sources), abnormal axis elongation (1 source), abnormal blastopore morphology (1 source), abnormal epidermis morphology (1 source), abnormal epidermis outer layer morphology (1 source), abnormal incomplete closing of the blastopore (1 source), abnormal mesodermal cell morphology (1 source), absent eye (1 source), absent head (1 source), decreased size of the eye (1 source), decreased size of the head (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: cdh3 manipulated (9 sources), cdh3 assayed (11 sources)
Computed annotations: cdh3 assayed (1 source)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + cdh3 MO (4 sources), Xla Wt + cdh3del_2240-2699 (3 sources), Xla Wt + cdh3 (2 sources), Xla Wt + cdh3 MO (2 sources), Xla Wt + cdh3 MO (2 sources), Xla Wt + cdh3del_2240-2699 (2 sources), Xla Wt + KD-Pak1 + cdh3 MO + cdh4 MO (2 sources), Xla Wt + cdh3 MO (1 source), Xla Wt + cdh3 MO (1 source), Xla Wt + cdh3del_2240-2699 (1 source), Xla Wt + cdh3del_2240-2699 (1 source), Xla Wt + KD-Pak1 + cdh3 MO (1 source), Xtr Wt + cdh3 MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (40 sources): Abnormality of dental morphology, Abnormality of limb bone morphology, Abnormality of macular pigmentation, Abnormality of retinal pigmentation, Abnormality of the orbital region, Abnormality of vision, Absent eyebrow, Blindness, Brittle hair, Camptodactyly, [+]
Mouse (5 sources): abnormal mammary gland development, abnormal mammary gland morphology, mammary gland alveolar hyperplasia, mammary gland duct hyperplasia, mammary gland hyperplasia

View all ortholog results at Monarch