foxc2 Phenotypes

Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Phenotypes

Gene Literature (27)

Nucleotides (193)

Interactants (560)

XB-GENEPAGE-481381

Gene Symbol: foxc2 Gene Name: forkhead box C2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: foxc2 assayed (21 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (34 sources): Abnormality of cardiovascular system morphology, Abnormality of the musculature, Abnormality of the pulmonary vasculature, Arrhythmia, Cataract, Cellulitis, Cleft palate, Cleft upper lip, Conjunctivitis, Corneal erosion, Corneal ulceration, Diabetes mellitus, Distichiasis, Ectropion, Fibrosarcoma, Glomerulopathy, Lymphedema, Muscle weakness, Patent ductus arteriosus, Photophobia, Predominantly lower limb lymphedema, Proteinuria, Ptosis, Recurrent corneal erosions, Recurrent skin infections, Recurrent urinary tract infections, Renal duplication, Spinal arachnoid cyst, Tetralogy of Fallot, Tubulointerstitial nephritis, Varicose veins, Ventricular septal defect, Webbed neck, Yellow nails [+]
Mouse (71 sources): abnormal Meckel's cartilage morphology, abnormal alisphenoid bone morphology, abnormal basisphenoid bone morphology, abnormal canal of Schlemm morphology, abnormal craniofacial bone morphology, abnormal fourth pharyngeal arch artery morphology, abnormal glomerular mesangium morphology, abnormal gonial bone morphology, abnormal iridocorneal angle, abnormal iris pigment epithelium, abnormal lymph circulation, abnormal malleus morphology, abnormal mesangial cell morphology, abnormal middle ear ossicle morphology, abnormal multipotent stem cell morphology, abnormal otic vesicle development, abnormal palatine bone horizontal plate morphology, abnormal podocyte morphology, abnormal presphenoid bone morphology, abnormal pterygoid process morphology, abnormal renal glomerulus basement membrane morphology, abnormal renal glomerulus morphology, abnormal somite shape, abnormal sphenoid bone morphology, abnormal supraoccipital bone morphology, abnormal third pharyngeal arch artery morphology, abnormal trabecular meshwork morphology, abnormal vertebral arch morphology, abnormal vertebral body morphology, absent cartilage, absent glomerular endothelium fenestra, absent incus, absent palatine bone, absent palatine bone horizontal plate, absent podocyte foot process, absent podocyte slit diaphragm, absent presphenoid bone, absent soft palate, absent supraoccipital bone, aortic arch coarctation, corneal abrasion, decreased glomerular capillary number, decreased renal glomerulus number, decreased tympanic ring size, dilated glomerular capillary, embryonic lethality during organogenesis, incomplete penetrance, enlarged lymph nodes, extremity edema, eye opacity, glomerulus hemorrhage, gonial bone hypoplasia, increased brown adipose tissue amount, increased lymph node number, kinked neural tube, lymphatic vessel hyperplasia, malleus hypoplasia, no abnormal phenotype detected, ocular distichiasis, perinatal lethality, complete penetrance, short vertebral body, small Meckel's cartilage, small basioccipital bone, small exoccipital bone, small interparietal bone, small kidney, small mandible, small pterygoid bone, small temporal bone squamous part, small vertebral body, spinal hemorrhage, thin myocardium [+]
View all ortholog results at Monarch