| Monarch Ortholog Phenotypes
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Human (38 sources):
Abdominal pain,
Abnormal bleeding,
Abnormal granulocytopoietic cell morphology,
Acute promyelocytic leukemia,
Alcoholism,
Anemia,
Anorexia,
Bone marrow hypercellularity,
Bone pain,
Bruising susceptibility,
Chronic infection,
Diffuse alveolar hemorrhage,
Disseminated intravascular coagulation,
Ecchymosis,
Epistaxis,
Exertional dyspnea,
Fatigue,
Fever,
Gangrene,
Gingival bleeding,
Gingival overgrowth,
Hematuria,
Hypofibrinogenemia,
Leukocytosis,
Leukopenia,
Lymphadenopathy,
Metrorrhagia,
Muscle weakness,
Neutropenia,
Oral cavity bleeding,
Pancytopenia,
Petechiae,
Productive cough,
Purpura,
Stomatitis,
Thrombocytopenia,
Vertigo,
Weight loss
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Mouse (22 sources):
abnormal alisphenoid bone morphology,
abnormal cervical axis morphology,
abnormal cervical vertebrae morphology,
abnormal incus morphology,
abnormal lymphopoiesis,
abnormal male germ cell apoptosis,
abnormal spermatid morphology,
abnormal spermiogenesis,
abnormal temporal bone squamous part morphology,
abnormal thyroid cartilage morphology,
abnormal tracheal cartilage morphology,
cervical vertebral transformation,
fusion of atlas and odontoid process,
fusion of vertebral arches,
interdigital webbing,
lumbar vertebral transformation,
neonatal lethality, incomplete penetrance,
no abnormal phenotype detected,
premature death,
seminiferous tubule degeneration,
thoracic vertebral transformation,
vertebral transformation
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.