fgf4 Phenotypes

Phenotypes

XB-GENEPAGE-480495

Gene Symbol: fgf4 Gene Name: fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene)

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
increased MAP kinase activity (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: fgf4 manipulated (2 sources), fgf4 assayed (7 sources)
Computed annotations: fgf4 assayed (3 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + fgf4 + animal cap explant (1 source), Xla Wt + fgf4 + animal cap explant (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (20 sources): abnormal digit development, abnormal egg cylinder morphology, abnormal embryo development, abnormal extraembryonic endoderm formation, abnormal limb development, broad limb buds, decreased grip strength, decreased inner cell mass proliferation, embryonic growth arrest, embryonic lethality between implantation and somite formation, complete penetrance, embryonic lethality prior to organogenesis, empty decidua capsularis, eyelid hyperplasia, limbs/digits/tail phenotype, no abnormal phenotype detected, polysyndactyly, prenatal lethality, preweaning lethality, complete penetrance, respiratory system phenotype, skeleton phenotype [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (20 sources): abnormal digit development, abnormal egg cylinder morphology, abnormal embryo development, abnormal extraembryonic endoderm formation, abnormal limb development, broad limb buds, decreased grip strength, decreased inner cell mass proliferation, embryonic growth arrest, embryonic lethality between implantation and somite formation, complete penetrance, [+]