onecut1 Phenotypes

Phenotypes

XB-GENEPAGE-480151

Gene Symbol: onecut1 Gene Name: one cut homeobox 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: onecut1 assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (34 sources): abnormal bile duct development, abnormal branching involved in pancreas development, abnormal endocrine pancreas development, abnormal hepatoblast differentiation, abnormal pancreas development, abnormal pancreatic acinus morphology, abnormal pancreatic duct morphology, abnormal pancreatic islet morphology, abnormal pancreatic primary cilium morphology, abnormal retina outer plexiform layer morphology, absent pancreatic alpha cells, absent pancreatic beta cells, absent pancreatic islets, decreased a-wave amplitude, decreased b-wave amplitude, decreased circulating glucose level, decreased pancreatic acinar cell number, decreased pancreatic alpha cell number, decreased pancreatic delta cell number, decreased pancreatic primary cilium number, dilated pancreatic duct, disorganized pancreatic islets, disorganized retina outer nuclear layer, endocrine/exocrine gland phenotype, exocrine pancreas atrophy, fetal growth retardation, homeostasis/metabolism phenotype, increased circulating glucose level, pancreatic acinar-to-ductal metaplasia, postnatal lethality, incomplete penetrance, retina outer nuclear layer degeneration, thin retina outer nuclear layer, thin retina outer plexiform layer, vision/eye phenotype [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (34 sources): abnormal bile duct development, abnormal branching involved in pancreas development, abnormal endocrine pancreas development, abnormal hepatoblast differentiation, abnormal pancreas development, abnormal pancreatic acinus morphology, abnormal pancreatic duct morphology, abnormal pancreatic islet morphology, abnormal pancreatic primary cilium morphology, abnormal retina outer plexiform layer morphology, [+]